TuringDB Logo
TuringDB Logo

Lightning-Fast Graph Analytics for Drug Discovery

Human biology is subject to billions of interacting components. TuringDB manages this complexity, offering auditable and explainable accelerated drug discovery, optimised clinical trials, and simulated biological systems.

Wireframe visualization of pharmaceutical capsule and molecular structure

Biology is a Complex System

Therapy responses vary based on individual biology, disease evolution, sex, exposures, nutrition, and more. This vast complexity results in frequent treatment failures.

A holistic approach demands multimodal data integration: omics, clinical data, EHR, and knowledge graphs. All of this can be represented visually.

Billions of Interactions

Spatially & dynamically interacting biological components

Multimodal Data

View connections between omics, clinical, EHR, and knowledge data

Individual Variability

Account for biology, disease evolution, and exposures

Built to Manage Complexity

These systems need multilayer representation that can deal with every abstraction of biology. Our reasoning AI & graph engine analyses, interprets, and simulates the mechanisms underlying drug response in individuals and groups.

Data & Knowledge Integration in Graphs

We build custom graph solutions for pharma and biotech companies with TuringDB Custom, unifying siloed data into actionable insights.

Unify siloed clinical, omics & trial data

Real-time insights at sub-ms speed

Built-in audit trail & compliance

Branch & simulate "what-if" scenarios

Power explainable AI & LLM grounding

Build-up or expand your internal AI capabilities

TuringDB Graph Engine Architecture showing data integration, pipelines, analytics, and knowledge graph with biological entities
Simulation of drug effects on oral tumor biopsy digital twin showing immune activity and spatial transcriptomics

Spatial Biology Simulation

Predict drug effects on individual patient biopsies using multilayer graph models that capture cell-cell interactions, spatial relationships, and molecular pathways.

Multilayer models for hot vs cold tumours

Personalised response prediction

Root cause and critical event analysis

Spatial and temporal event prediction

Mechanisms of Action Analysis

Characterize & simulate mechanisms, synergetic effects, and drugs to increase safety & efficacy. Build rationale based on data and knowledge of mechanisms for new drugs or repurposed drugs.

Identify synergetic drug combinations

Map immune circuit interactions

Discover novel mechanisms of action

Predict drug safety & efficacy profiles

Complex mechanisms of action network showing drug targets, biological pathways, and gene-protein interactions

Biopharma Applications

Spatial Omics Integration

Integrate multimodal spatial data (10X Visium, IF Multiplex, H&E) to analyse cell-cell spatial interaction networks and tumour microenvironment dynamics.

• Cell-cell interaction mapping

• TME spatial analysis

• Multi-cohort validation

Target & Drug Prioritisation

Identify and prioritise drug targets through automated reasoning paths with evidence, simulating biological responses to novel and repurposed drugs.

• 545+ drug candidates analysed

• Novel mechanism discovery

• Patient group stratification

Drug Combination Analysis

Build causal graphs to analyse drug combinations and predict synergistic effects on downstream cellular interactions in responder vs non-responder patients.

• Immunotherapy combinations

• Logical reasoning paths

• Mechanism of action mapping

Knowledge Graphs

Build comprehensive knowledge graphs connecting genes, proteins, diseases, and compounds for faster target identification and pathway analysis.

• Multi-omics data integration

• Pathway analysis at scale

• Real-time hypothesis testing

Clinical Trials

Optimise patient recruitment and trial design by analysing complex relationships in clinical data and predicting adverse events.

• Patient cohort identification

• Adverse event prediction

• Trial site optimisation

Drug Repurposing

Discover new therapeutic applications for existing drugs through deep graph traversals and mechanism of action discovery.

• Drug-disease relationship mapping

• Side effect similarity analysis

• Novel indication discovery

Why Use TuringDB for Biopharma?

Sub-Millisecond Query Performance

Analyse millions of biological entities and their relationships in real time. Run complex multi-hop queries on protein interaction networks, metabolic pathways, and disease associations without waiting.

Auditable & Explainable

Built with critical industries like healthcare in mind. Track every reasoning path, maintain full audit trails, and ensure explainable AI for regulatory compliance.

Deep Graph Traversals

Run deep graph traversals and multihops on large graphs to simulate complex biology. Analyse cell-cell interactions, spatial relationships, and temporal dynamics at scale.

Enterprise Security

Deploy on-premises or in your VPC with full control over sensitive research data. Meet HIPAA, GDPR, and other regulatory requirements with built-in security features.

Ready to Transform Your Drug Discovery?

Join the leading biopharma companies using TuringDB to accelerate research and bring therapies to patients faster.